Unchanged triclabendazole kinetics after co-administration with ivermectin and methimazole: failure of its therapeutic activity against triclabendazole-resistant liver flukes
<p>Abstract</p> <p>Background</p> <p>The reduced drug accumulation based on enhanced drug efflux and metabolic capacity, identified in triclabendazole (TCBZ)-resistant <it>Fasciola hepatica </it>may contribute to the development of resistance to TCBZ. The ai...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2010-02-01
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Series: | BMC Veterinary Research |
Online Access: | http://www.biomedcentral.com/1746-6148/6/8 |