Unchanged triclabendazole kinetics after co-administration with ivermectin and methimazole: failure of its therapeutic activity against triclabendazole-resistant liver flukes

<p>Abstract</p> <p>Background</p> <p>The reduced drug accumulation based on enhanced drug efflux and metabolic capacity, identified in triclabendazole (TCBZ)-resistant <it>Fasciola hepatica </it>may contribute to the development of resistance to TCBZ. The ai...

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Bibliographic Details
Main Authors: Shaw Laura, Alvarez Luis, Moreno Laura, Ceballos Laura, Fairweather Ian, Lanusse Carlos
Format: Article
Language:English
Published: BMC 2010-02-01
Series:BMC Veterinary Research
Online Access:http://www.biomedcentral.com/1746-6148/6/8