Angiotensin-(1–7) Promotes Resolution of Eosinophilic Inflammation in an Experimental Model of Asthma

Angiotensin-(1–7) Promotes Resolution of Eosinophilic Inflammation in an Experimental Model of Asthma

Defective apoptosis of eosinophils, the main leukocyte in the pathogenesis of asthma, and delay in its removal lead to lung damage and loss of pulmonary function due to failure in the resolution of inflammation. Here, we investigated the ability of angiotensin-(1–7) [Ang-(1–7)], a pivotal peptide of...

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Bibliographic Details
Main Authors: Giselle S. Magalhaes, Lívia C. Barroso, Alesandra C. Reis, Maria G. Rodrigues-Machado, Juliana F. Gregório, Daisy Motta-Santos, Aline C. Oliveira, Denise A. Perez, Lucíola S. Barcelos, Mauro M. Teixeira, Robson A. S. Santos, Vanessa Pinho, Maria Jose Campagnole-Santos
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-01-01
Series:Frontiers in Immunology
Subjects:
Mas receptor
apoptosis
efferocytosis
caspase 3
GATA3
NF-kB
Online Access:http://journal.frontiersin.org/article/10.3389/fimmu.2018.00058/full

Internet

http://journal.frontiersin.org/article/10.3389/fimmu.2018.00058/full

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