Functions and regulation of lipocalin-2 in gut-origin sepsis: a narrative review

Abstract Lipocalin-2 (Lcn2), an innate immune protein, has come to be recognized for its roles in iron homeostasis, infection, and inflammation. In this narrative review, we provide a comprehensive description based on currently available evidence of the clinical implications of Lcn2 and its therape...

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Bibliographic Details
Main Authors: Fanglin Lu, Kei Inoue, Jungo Kato, Shizuka Minamishima, Hiroshi Morisaki
Format: Article
Language:English
Published: BMC 2019-08-01
Series:Critical Care
Subjects:
Online Access:http://link.springer.com/article/10.1186/s13054-019-2550-2