PCSK9 and the nervous system: a no-brainer?

In the past 20 years, PCSK9 has been shown to play a pivotal role in LDL cholesterol metabolism and cardiovascular health by inducing the lysosomal degradation of the LDL receptor. PCSK9 was discovered by the cloning of genes up-regulated after apoptosis induced by serum deprivation in primary cereb...

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Bibliographic Details
Main Authors: Ali K. Jaafar, Romuald Techer, Kévin Chemello, Gilles Lambert, Steeve Bourane
Format: Article
Language:English
Published: Elsevier 2023-09-01
Series:Journal of Lipid Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227523000998