Manganese Accumulation in the Brain via Various Transporters and Its Neurotoxicity Mechanisms
Manganese (Mn) is an essential trace element, serving as a cofactor for several key enzymes, such as glutamine synthetase, arginase, pyruvate decarboxylase, and mitochondrial superoxide dismutase. However, its chronic overexposure can result in a neurological disorder referred to as manganism, prese...
Main Authors: | Ivan Nyarko-Danquah, Edward Pajarillo, Alexis Digman, Karam F. A. Soliman, Michael Aschner, Eunsook Lee |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2020-12-01
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Series: | Molecules |
Subjects: | |
Online Access: | https://www.mdpi.com/1420-3049/25/24/5880 |
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