Manganese Accumulation in the Brain via Various Transporters and Its Neurotoxicity Mechanisms

Manganese Accumulation in the Brain via Various Transporters and Its Neurotoxicity Mechanisms

Manganese (Mn) is an essential trace element, serving as a cofactor for several key enzymes, such as glutamine synthetase, arginase, pyruvate decarboxylase, and mitochondrial superoxide dismutase. However, its chronic overexposure can result in a neurological disorder referred to as manganism, prese...

Полное описание

Библиографические подробности
Главные авторы:	Ivan Nyarko-Danquah, Edward Pajarillo, Alexis Digman, Karam F. A. Soliman, Michael Aschner, Eunsook Lee
Формат:	Статья
Язык:	English
Опубликовано:	MDPI AG 2020-12-01
Серии:	Molecules
Предметы:	manganese DMT1 ZIP4 ZIP8 oxidative stress inflammation
Online-ссылка:	https://www.mdpi.com/1420-3049/25/24/5880

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