Minimal residual disease guided radical chemoradiotherapy combined with immunotherapy after neoadjuvant immunochemotherapy followed by adjuvant immunotherapy for esophageal squamous cell cancer (ECMRD-001): a study protocol for a prospective cohort study

Minimal residual disease guided radical chemoradiotherapy combined with immunotherapy after neoadjuvant immunochemotherapy followed by adjuvant immunotherapy for esophageal squamous cell cancer (ECMRD-001): a study protocol for a prospective cohort study

IntroductionFor locally advanced, inoperable esophageal cancer, concurrent chemoradiotherapy (CCRT) becomes the norm. Combining immunotherapy with radiotherapy has been shown to improve efficacy. Circulating tumor DNA (ctDNA) is a strong predictor of effectiveness and tumor recurrence and is indicat...

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Bibliographic Details
Main Authors: Hesong Wang, Xueyuan Zhang, Xiaohan Zhao, Chunyang Song, Wenzhao Deng, Wenbin Shen
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-01-01
Series:Frontiers in Immunology
Subjects:
circulating tumor DNA
ctDNA
minimal residual disease
MRD
esophageal cancer
esophageal carcinoma
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1330928/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2023.1330928/full

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