Can Be miR-126-3p a Biomarker of Premature Aging? An Ex Vivo and In Vitro Study in Fabry Disease

Can Be miR-126-3p a Biomarker of Premature Aging? An Ex Vivo and In Vitro Study in Fabry Disease

Fabry disease (FD) is a lysosomal storage disorder (LSD) characterized by lysosomal accumulation of glycosphingolipids in a wide variety of cytotypes, including endothelial cells (ECs). FD patients experience a significantly reduced life expectancy compared to the general population; therefore, the...

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Bibliographic Details
Main Authors: Alessia Lo Curto, Simona Taverna, Maria Assunta Costa, Rosa Passantino, Giuseppa Augello, Giorgia Adamo, Anna Aiello, Paolo Colomba, Carmela Zizzo, Marco Zora, Giulia Accardi, Giuseppina Candore, Daniele Francofonte, Tiziana Di Chiara, Riccardo Alessandro, Calogero Caruso, Giovanni Duro, Giuseppe Cammarata
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:Cells
Subjects:
Fabry disease
microRNA
miR-126-3p
small extracellular vesicles
aging
senescence
Online Access:https://www.mdpi.com/2073-4409/10/2/356

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https://www.mdpi.com/2073-4409/10/2/356

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