Endothelial cell cycle state determines propensity for arterial-venous fate

During blood vessel development, endothelial cells become specified toward arterial or venous fates. Chavkin et al find that distinct endothelial cell cycle states provide windows of opportunity for the molecular induction of arterial or venous fate.

Bibliographic Details
Main Authors: Nicholas W. Chavkin, Gael Genet, Mathilde Poulet, Erin D. Jeffery, Corina Marziano, Nafiisha Genet, Hema Vasavada, Elizabeth A. Nelson, Bipul R. Acharya, Anupreet Kour, Jordon Aragon, Stephanie P. McDonnell, Mahalia Huba, Gloria M. Sheynkman, Kenneth Walsh, Karen K. Hirschi
Format: Article
Language:English
Published: Nature Portfolio 2022-10-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-022-33324-7