Mouse Models of Frequently Mutated Genes in Acute Myeloid Leukemia

Mouse Models of Frequently Mutated Genes in Acute Myeloid Leukemia

Acute myeloid leukemia is a clinically and biologically heterogeneous blood cancer with variable prognosis and response to conventional therapies. Comprehensive sequencing enabled the discovery of recurrent mutations and chromosomal aberrations in AML. Mouse models are essential to study the biologi...

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Bibliographic Details
Main Authors: Sagarajit Mohanty, Michael Heuser
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:Cancers
Subjects:
AML
synergy
leukemia
mutations
transgenic mice
mouse models
Online Access:https://www.mdpi.com/2072-6694/13/24/6192

Internet

https://www.mdpi.com/2072-6694/13/24/6192

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