Impact of genotyping errors on the type I error rate and the power of haplotype-based association methods

<p>Abstract</p> <p>Background</p> <p>We investigated the influence of genotyping errors on the type I error rate and empirical power of two haplotype based association methods applied to candidate regions. We compared the performance of the Mantel Statistic Using Haplot...

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Bibliographic Details
Main Authors: Lamina Claudia, Heid Iris M, Beckmann Lars, Marquard Vivien, Chang-Claude Jenny
Format: Article
Language:English
Published: BMC 2009-01-01
Series:BMC Genetics
Online Access:http://www.biomedcentral.com/1471-2156/10/3