Histological analysis of nucleus pulposus tissue from patients with lumbar disc herniation after condoliase administration

Histological analysis of nucleus pulposus tissue from patients with lumbar disc herniation after condoliase administration

Abstract Background Condoliase is an enzyme used as a treatment for lumbar disc herniation (LDH). This enzyme degrades chondroitin sulfate (CS) in the nucleus pulposus of the intervertebral disc (IVD). However, there are cases in which symptoms do not improve, despite condoliase administration. This...

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Bibliographic Details
Main Authors: Yuka Minamisawa, Taiichi Shirogane, Ippei Watanabe, Akira Dezawa
Format: Article
Language:English
Published: Wiley 2024-06-01
Series:JOR Spine
Subjects:
chemonucleolysis
chondroitin sulfate
condoliase
immunohistochemistry
lumbar disc herniation
Online Access:https://doi.org/10.1002/jsp2.1328

Internet

https://doi.org/10.1002/jsp2.1328

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