Guanabenz acetate, an antihypertensive drug repurposed as an inhibitor of Escherichia coli biofilm
ABSTRACT Biofilms formed by Escherichia coli are composed of amyloid curli and cellulose and have been shown to be linked to pathogenicity, antibiotic resistance, and chronic infections. Guanabenz acetate (GABE), an antihypertensive drug, was identified as a potential strategic repurposing drug due...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
American Society for Microbiology
2024-11-01
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Series: | Microbiology Spectrum |
Subjects: | |
Online Access: | https://journals.asm.org/doi/10.1128/spectrum.00738-24 |