B-arrestin-2 Signaling Is Important to Preserve Cardiac Function During Aging

B-arrestin-2 Signaling Is Important to Preserve Cardiac Function During Aging

Experiments reported here tested the hypothesis that β-arrestin-2 is an important element in the preservation of cardiac function during aging. We tested this hypothesis by aging β-arrestin-2 knock-out (KO) mice, and wild-type equivalent (WT) to 12–16months. We developed the rationale for these expe...

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Bibliographic Details
Main Authors: Andrielle E. Capote, Ashley Batra, Chad M. Warren, Shamim A. K. Chowdhury, Beata M. Wolska, R. John Solaro, Paola C. Rosas
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-08-01
Series:Frontiers in Physiology
Subjects:
β-arrestin-2
cardiac dysfunction
angiotensin
cardiac myosin binding protein-C
myosin regulatory light chain
Online Access:https://www.frontiersin.org/articles/10.3389/fphys.2021.696852/full

Internet

https://www.frontiersin.org/articles/10.3389/fphys.2021.696852/full

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