Description of Osmolyte Pathways in Maturing <i>Mdx</i> Mice Reveals Altered Levels of Taurine and Sodium/Myo-Inositol Co-Transporters

Description of Osmolyte Pathways in Maturing <i>Mdx</i> Mice Reveals Altered Levels of Taurine and Sodium/Myo-Inositol Co-Transporters

Duchenne muscular dystrophy (DMD) is a genetic disorder characterized by progressive muscle degeneration. Osmotic stress participates to DMD pathology and altered levels of osmolyte pathway members have been reported. The goal of this study was to gain insight in osmoregulatory changes in the <i&...

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Bibliographic Details
Main Authors: Caroline Merckx, Gwenny Cosemans, Jana Zschüntzsch, Robrecht Raedt, Jens Schmidt, Boel De Paepe, Jan L. De Bleecker
Format: Article
Language:English
Published: MDPI AG 2022-03-01
Series:International Journal of Molecular Sciences
Subjects:
Duchenne muscular dystrophy
<i>mdx</i>
osmoregulation
taurine transporter
sodium myo-inositol transporter
aldose reductase
Online Access:https://www.mdpi.com/1422-0067/23/6/3251

Internet

https://www.mdpi.com/1422-0067/23/6/3251

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