Cytotoxic and apoptosis-inducing effects of wildtype and mutated Hydra actinoporin-like toxin 1 (HALT-1) on various cancer cell lines

Background Hydra actinoporin like toxin -1 (HALT-1), is a small 18.5 kDa pore forming toxin derived from Hydra magnipapillata which has been shown to elicit strong haemolytic and cytolytic activity when in contact with cell membranes. Due to its cytotoxic potency, HALT-1 was further investigated for...

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Bibliographic Details
Main Authors: Teng Jia Ng, Michelle Yee Mun Teo, Dek Shen Liew, Paul Etim Effiong, Jung Shan Hwang, Crystale Siew Ying Lim, Lionel L.A. In
Format: Article
Language:English
Published: PeerJ Inc. 2019-05-01
Series:PeerJ
Subjects:
Online Access:https://peerj.com/articles/6639.pdf