Adult Camk2a gene reinstatement restores the learning and plasticity deficits of Camk2a knockout mice

Adult Camk2a gene reinstatement restores the learning and plasticity deficits of Camk2a knockout mice

Summary: With the recent findings that mutations in the gene encoding the α-subunit of calcium/calmodulin-dependent protein kinase II (CAMK2A) causes a neurodevelopmental disorder (NDD), it is of great therapeutic relevance to know if there exists a critical developmental time window in which CAMK2A...

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Bibliographic Details
Main Authors: Pomme M.F. Rigter, Ilse Wallaard, Mehrnoush Aghadavoud Jolfaei, Jenina Kingma, Laura Post, Minetta Elgersma, Ype Elgersma, Geeske M. van Woerden
Format: Article
Language:English
Published: Elsevier 2022-11-01
Series:iScience
Subjects:
Cellular neuroscience
Cell biology
Developmental biology
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004222015759

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http://www.sciencedirect.com/science/article/pii/S2589004222015759

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