Cannabidiol Enhances Cabozantinib-Induced Apoptotic Cell Death via Phosphorylation of p53 Regulated by ER Stress in Hepatocellular Carcinoma

Cannabidiol Enhances Cabozantinib-Induced Apoptotic Cell Death via Phosphorylation of p53 Regulated by ER Stress in Hepatocellular Carcinoma

Cannabidiol (CBD), a primary constituent in hemp and cannabis, exerts broad pharmacological effects against various diseases, including cancer. Additionally, cabozantinib, a potent multi-kinase inhibitor, has been approved for treating patients with advanced hepatocellular carcinoma (HCC). Recently,...

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Bibliographic Details
Main Authors: Youngsic Jeon, Taejung Kim, Hyukjoon Kwon, Jeong-Kook Kim, Young-Tae Park, Jungyeob Ham, Young-Joo Kim
Format: Article
Language:English
Published: MDPI AG 2023-08-01
Series:Cancers
Subjects:
cannabidiol
cabozantinib
apoptosis
p53
endoplasmic reticulum stress
Online Access:https://www.mdpi.com/2072-6694/15/15/3987

Internet

https://www.mdpi.com/2072-6694/15/15/3987

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