Single injection of very mild dose botulinum toxin in the vastus lateralis improves testicular spermatogenesis and sperm motility in ageing experimental mice

Single injection of very mild dose botulinum toxin in the vastus lateralis improves testicular spermatogenesis and sperm motility in ageing experimental mice

Abstract Background Botulinum toxin (BoNT) is a widely used therapeutic agent that blocks the excessive release of acetylcholine at the neuromuscular junction. Previously, repeated intracremasteric injections and slight overdose of BoNT have been reported to induce adverse effects in the testicular...

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Bibliographic Details
Main Authors: Risna Kanjirassery Radhakrishnan, Sowbarnika Ravichandran, Aishwarya Sukesh, Balamuthu Kadalmani, Mahesh Kandasamy
Format: Article
Language:English
Published: BMC 2022-03-01
Series:Laboratory Animal Research
Subjects:
BoNT
Acetylcholine
Spermatogenesis
Testis
Sperm
Antioxidants
Online Access:https://doi.org/10.1186/s42826-022-00117-4

Internet

https://doi.org/10.1186/s42826-022-00117-4

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