Local and systemic immune responses induced by intranasal immunization with biomineralized foot-and-mouth disease virus-like particles

Local and systemic immune responses induced by intranasal immunization with biomineralized foot-and-mouth disease virus-like particles

IntroductionFoot-and-mouth disease virus (FMDV) infects the host by invading mucosal epithelial cells of the respiratory or digestive tract. Therefore, establishing a specific antiviral mucosal immune barrier can effectively block viral invasion.MethodsWe evaluated local mucosal and systemic immune...

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Bibliographic Details
Main Authors: Shuo Li, Ruichong Zhao, Hetao Song, Songjia Pan, Yun Zhang, Hu Dong, Manyuan Bai, Shiqi Sun, Huichen Guo, Shuanghui Yin
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-02-01
Series:Frontiers in Microbiology
Subjects:
foot-and-mouth disease virus
biomineralization
virus-like particles
mucosal immunity
adjuvant
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2023.1112641/full

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https://www.frontiersin.org/articles/10.3389/fmicb.2023.1112641/full

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