Kidney function and daily emtricitabine/tenofovir disoproxil fumarate pre-exposure prophylaxis against HIV: results from the real-life multicentric demonstrative project PrEP Brazil

Abstract Background Pre-Exposure Prophylaxis (PrEP) has demonstrated efficacy in the reduction of sexually transmitted HIV infections. The prolonged use of tenofovir disoproxil fumarate (TDF) and emtricitabine (FTC) co-formulation (TDF/FTC), however, may result in augmented risk of renal toxicity. W...

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Main Authors: Karla Cristina Silva Petruccelli, Djane Clarys Baía-da-Silva, Fernando Val, Monica Santos Valões, Nadia Cubas-Vega, Alexandre Vilhena Silva-Neto, Vanderson Sampaio, Aline Alencar, Roberto Pecoits-Filho, Rodrigo Carvalho Moreira, Sandra Wagner Cardoso, Ronaldo I. Moreira, Iuri Costa Leite, José Valdez Madruga, Esper G. Kallas, Paulo R. Alencastro, Brenda Hoagland, Beatriz Grinsztejn, Valdiléa Gonçalves Veloso Santos, Marcus Vinícius Guimarães Lacerda
Format: Article
Language:English
Published: BMC 2022-02-01
Series:AIDS Research and Therapy
Subjects:
Online Access:https://doi.org/10.1186/s12981-022-00437-4