The role of the genomic mutation signature and tumor mutation burden on relapse risk prediction in head and neck squamous cell carcinoma after concurrent chemoradiotherapy

The role of the genomic mutation signature and tumor mutation burden on relapse risk prediction in head and neck squamous cell carcinoma after concurrent chemoradiotherapy

Abstract Personalized genetic profiling has focused on improving treatment efficacy and predicting risk stratification by identifying mutated genes and selecting targeted agents according to genetic testing. Therefore, we evaluated the role of genetic profiling and tumor mutation burden (TMB) using...

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Bibliographic Details
Main Authors: Hui-Ching Wang, Sin-Hua Moi, Leong-Perng Chan, Chun-Chieh Wu, Jeng-Shiun Du, Pei-Lin Liu, Meng-Chun Chou, Che-Wei Wu, Chih-Jen Huang, Hui-Hua Hsiao, Mei-Ren Pan, Li-Tzong Chen
Format: Article
Language:English
Published: Nature Publishing Group 2023-05-01
Series:Experimental and Molecular Medicine
Online Access:https://doi.org/10.1038/s12276-023-00984-4

Internet

https://doi.org/10.1038/s12276-023-00984-4

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