SMTP-44D Exerts Antioxidant and Anti-Inflammatory Effects through Its Soluble Epoxide Hydrolase Inhibitory Action in Immortalized Mouse Schwann Cells upon High Glucose Treatment

SMTP-44D Exerts Antioxidant and Anti-Inflammatory Effects through Its Soluble Epoxide Hydrolase Inhibitory Action in Immortalized Mouse Schwann Cells upon High Glucose Treatment

Diabetic neuropathy (DN) is a major complication of diabetes mellitus. We have previously reported the efficacy of <i>Stachybotrys microspora</i> triprenyl phenol-44D (SMTP-44D) for DN through its potential antioxidant and anti-inflammatory activities. However, the mechanisms underlying...

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Bibliographic Details
Main Authors: Ryosuke Shinouchi, Keita Shibata, Shiori Jono, Keiji Hasumi, Koji Nobe
Format: Article
Language:English
Published: MDPI AG 2022-05-01
Series:International Journal of Molecular Sciences
Subjects:
diabetic neuropathy
IMS32
Schwann cell
soluble epoxide hydrolase
epoxyeicosatrienoic acid
antioxidant
Online Access:https://www.mdpi.com/1422-0067/23/9/5187

Internet

https://www.mdpi.com/1422-0067/23/9/5187

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