Anticancer Agents Targeted to Sirtuins

Anticancer Agents Targeted to Sirtuins

Sirtuins are nicotinamide adenine dinucleotide+-dependent deacetylases of which there are seven isoforms (SIRT1–7). Sirtuin activity is linked to gene expression, lifespan extension, neurodegeneration, and age-related disorders. Numerous studies have suggested that sirtuins could be of great signifi...

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Bibliographic Details
Main Authors: Tomohiro Kozako, Takayoshi Suzuki, Makoto Yoshimitsu, Naomichi Arima, Shin-ichiro Honda, Shinji Soeda
Format: Article
Language:English
Published: MDPI AG 2014-12-01
Series:Molecules
Subjects:
sirtuins
cancer
apoptosis
autophagy
Online Access:http://www.mdpi.com/1420-3049/19/12/20295

Internet

http://www.mdpi.com/1420-3049/19/12/20295

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