Immunoregulatory effects of Tetrastigma hemsleyanum polysaccharide via TLR4-mediated NF-κB and MAPK signaling pathways in Raw264.7 macrophages

Immunoregulatory effects of Tetrastigma hemsleyanum polysaccharide via TLR4-mediated NF-κB and MAPK signaling pathways in Raw264.7 macrophages

Polysaccharide of Tetrastigma hemsleyanum (THP) exert antioxidant, antibacterial, lipid-lowering, and anti-inflammatory properties, especially some evidences have highlighted the efficiency of it as an anti-tumor agent. However, as a biological macromolecule with bidirectional immune regulation, the...

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Bibliographic Details
Main Authors: Jiayuan Wu, Juanfen Mo, Wei Xiang, Xiaowen Shi, Li Guo, Yi Li, Yi Bao, Li Zheng
Format: Article
Language:English
Published: Elsevier 2023-05-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Tetrastigma hemsleyanum
Polysaccharide
Immunomodulatory activity
NF-κB
MAPK
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332223002597

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http://www.sciencedirect.com/science/article/pii/S0753332223002597

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