Prevalence of common α-thalassemia determinants in south Brazil: importance for the diagnosis of microcytic anemia

Prevalence of common α-thalassemia determinants in south Brazil: importance for the diagnosis of microcytic anemia

Alpha thalassemia has not been systematically investigated in Brazil. In this study, 493 unrelated individuals from the southernmost Brazilian state of Rio Grande do Sul were screened for deletional forms of &#945;-thalassemia. One hundred and one individuals had microcytic anemia (MCV < 80 f...

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Bibliographic Details
Main Authors: Sandrine C. Wagner, Simone M. de Castro, Tatiana P. Gonzalez, Ana P. Santin, Leticia Filippon, Carina F. Zaleski, Laura A. Azevedo, Bruna Amorin, Sidia M. Callegari-Jacques, Mara H. Hutz
Format: Article
Language:English
Published: Sociedade Brasileira de Genética 2010-01-01
Series:Genetics and Molecular Biology
Subjects:
alpha-thalassemia
Brazilian population
genotype
hemoglobin
microcytosis
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572010000400008

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572010000400008

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