Bioreactor-Grown Bacillus of Calmette and Guérin (BCG) Vaccine Protects Badgers against Virulent <i>Mycobacterium bovis</i> When Administered Orally: Identifying Limitations in Baited Vaccine Delivery

Bioreactor-Grown Bacillus of Calmette and Guérin (BCG) Vaccine Protects Badgers against Virulent <i>Mycobacterium bovis</i> When Administered Orally: Identifying Limitations in Baited Vaccine Delivery

Bovine tuberculosis (TB) in Great Britain adversely affects animal health and welfare and is a cause of considerable economic loss. The situation is exacerbated by European badgers (<i>Meles meles</i>) acting as a wildlife source of recurrent <i>Mycobacterium bovis</i> infect...

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Bibliographic Details
Main Authors: Sandrine Lesellier, Colin P. D. Birch, Dipesh Davé, Deanna Dalley, Sonya Gowtage, Simonette Palmer, Claire McKenna, Gareth A. Williams, Roland Ashford, Ute Weyer, Sarah Beatham, Julia Coats, Alex Nunez, Pedro Sanchez-Cordon, John Spiropoulos, Stephen Powell, Jason Sawyer, Jordan Pascoe, Charlotte Hendon-Dunn, Joanna Bacon, Mark A. Chambers
Format: Article
Language:English
Published: MDPI AG 2020-08-01
Series:Pharmaceutics
Subjects:
BCG
oral vaccine
tuberculosis
badgers
bait
fermentation
Online Access:https://www.mdpi.com/1999-4923/12/8/782

Internet

https://www.mdpi.com/1999-4923/12/8/782

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