Transcription factor OTX2 silences the expression of cleavage embryo genes and transposable elements
Upon mammalian fertilization, zygotic genome activation (ZGA) and activation of transposable elements (TEs) occur in early embryos to establish totipotency and support embryogenesis. However, the molecular mechanisms controlling the expression of these genes in mammals remain poorly understood. The...
Główni autorzy: | , , , |
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Format: | Artykuł |
Język: | English |
Wydane: |
The Society for Reproduction and Development
2021-04-01
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Seria: | The Journal of Reproduction and Development |
Hasła przedmiotowe: | |
Dostęp online: | https://www.jstage.jst.go.jp/article/jrd/67/3/67_2021-007/_pdf/-char/en |