Phosphoproteomic Analysis Reveals a Different Proteomic Profile in Pediatric Patients With T-Cell Lymphoblastic Lymphoma or T-Cell Acute Lymphoblastic Leukemia

Phosphoproteomic Analysis Reveals a Different Proteomic Profile in Pediatric Patients With T-Cell Lymphoblastic Lymphoma or T-Cell Acute Lymphoblastic Leukemia

T-cell lymphoblastic lymphoma (T-LBL) and lymphoblastic leukemia (T-ALL) arise from the transformation of precursor T-cells sharing common morphological and immunophenotypic features. Despite this, T-LBL and T-ALL show different genomic/transcriptomic profiles and whether they represent two distinct...

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Bibliographic Details
Main Authors: Giulia Veltri, Federica Lovisa, Giuliana Cortese, Marta Pillon, Elisa Carraro, Simone Cesaro, Massimo Provenzi, Salvatore Buffardi, Samuela Francescato, Alessandra Biffi, Barbara Buldini, Valentino Conter, Valentina Serafin, Lara Mussolin
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-07-01
Series:Frontiers in Oncology
Subjects:
T-LBL
T-ALL
phosphoproteomics analysis
AKT/mTOR
JAK/STAT (janus kinase/signal transducer and activator of transcription)
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2022.913487/full

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https://www.frontiersin.org/articles/10.3389/fonc.2022.913487/full

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