Modulation of dipeptidyl peptidase IV by Rooibos tea metabolites towards type 2 diabetes care: Evidence from molecular dynamics simulation and density functional theory

Modulation of dipeptidyl peptidase IV by Rooibos tea metabolites towards type 2 diabetes care: Evidence from molecular dynamics simulation and density functional theory

Despite the reported antidiabetic potential of Rooibos tea, there is still paucity of information on its mechanisms of action to date. This study investigated the antidiabetic potential of Rooibos tea using computational approaches focusing on dipeptidyl peptidase (DPP-IV) implicated in insulin prod...

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Bibliographic Details
Main Authors: Lukman HY, Aribisala JO, Akoonjee A, Sulyman AO, Wudil AM, Sabiu S
Format: Article
Language:English
Published: Elsevier 2024-06-01
Series:Scientific African
Subjects:
Rooibos tea
Metabolites
Type 2 diabetes mellitus
Dipeptidyl peptidase-IV
Molecular dynamics simulation
Density functional theory
Online Access:http://www.sciencedirect.com/science/article/pii/S2468227624001182

Internet

http://www.sciencedirect.com/science/article/pii/S2468227624001182

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