Physicochemical stability of compounded midazolam capsules over a one-year storage period
In patients suffering from chronic liver disease, the hepatic metabolism of drugs is perturbed and the metabolic capacity is difficult to assess. Midazolam could be used as a phenotypical probe to predict the metabolic capacity of CYP3A to adjust dosages of drug substrates of this cytochrome. In thi...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
De Gruyter
2020-05-01
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Series: | Pharmaceutical Technology in Hospital Pharmacy |
Subjects: | |
Online Access: | https://doi.org/10.1515/pthp-2020-0015 |