Physicochemical stability of compounded midazolam capsules over a one-year storage period

In patients suffering from chronic liver disease, the hepatic metabolism of drugs is perturbed and the metabolic capacity is difficult to assess. Midazolam could be used as a phenotypical probe to predict the metabolic capacity of CYP3A to adjust dosages of drug substrates of this cytochrome. In thi...

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Bibliographic Details
Main Authors: Boivin Pierre-Nicolas, Legendre Pauline, Bonnaure Anne-Claire, Lester Marie-Antoinette
Format: Article
Language:English
Published: De Gruyter 2020-05-01
Series:Pharmaceutical Technology in Hospital Pharmacy
Subjects:
Online Access:https://doi.org/10.1515/pthp-2020-0015