A Standardized Botanical Composition Mitigated Acute Inflammatory Lung Injury and Reduced Mortality through Extracellular HMGB1 Reduction

A Standardized Botanical Composition Mitigated Acute Inflammatory Lung Injury and Reduced Mortality through Extracellular HMGB1 Reduction

HMGB1 is a key late inflammatory mediator upregulated during air-pollution-induced oxidative stress. Extracellular HMGB1 accumulation in the airways and lungs plays a significant role in the pathogenesis of inflammatory lung injury. Decreasing extracellular HMBG1 levels may restore innate immune cel...

Bibliografski detalji
Glavni autori:	Mesfin Yimam, Teresa Horm, Alexandria O’Neal, Ping Jiao, Mei Hong, Lidia Brownell, Qi Jia, Mosi Lin, Alex Gauthier, Jiaqi Wu, Kranti Venkat Mateti, Xiaojian Yang, Katelyn Dial, Sidorela Zefi, Lin L. Mantell
Format:	Članak
Jezik:	English
Izdano:	MDPI AG 2023-09-01
Serija:	Molecules
Teme:	HMGB1 inflammatory lung injury oxidative stress sepsis
Online pristup:	https://www.mdpi.com/1420-3049/28/18/6560

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