LDL Receptor Pathway Regulation by miR-224 and miR-520d

LDL Receptor Pathway Regulation by miR-224 and miR-520d

MicroRNAs (miRNA) have emerged as important post-transcriptional regulators of metabolic pathways that contribute to cellular and systemic lipoprotein homeostasis. Here, we identify two conserved miRNAs, miR-224, and miR-520d, which target gene networks regulating hepatic expression of the low-densi...

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Bibliographic Details
Main Authors: Alessandro G. Salerno, Coen van Solingen, Elena Scotti, Amarylis C. B. A. Wanschel, Milessa S. Afonso, Scott R. Oldebeken, Westley Spiro, Peter Tontonoz, Katey J. Rayner, Kathryn J. Moore
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-05-01
Series:Frontiers in Cardiovascular Medicine
Subjects:
noncoding RNA
low-density lipoprotein
cholesterol
PCSK9
IDOL
HMGCR
Online Access:https://www.frontiersin.org/article/10.3389/fcvm.2020.00081/full

Internet

https://www.frontiersin.org/article/10.3389/fcvm.2020.00081/full

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