Efficient Generation of Cardiac Purkinje Cells from ESCs by Activating cAMP Signaling

Efficient Generation of Cardiac Purkinje Cells from ESCs by Activating cAMP Signaling

Dysfunction of the specialized cardiac conduction system (CCS) is associated with life-threatening arrhythmias. Strategies to derive CCS cells, including rare Purkinje cells (PCs), would facilitate models for mechanistic studies and drug discovery and also provide new cellular materials for regenera...

Full description

Bibliographic Details
Main Authors: Su-Yi Tsai, Karen Maass, Jia Lu, Glenn I. Fishman, Shuibing Chen, Todd Evans
Format: Article
Language:English
Published: Elsevier 2015-06-01
Series:Stem Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2213671115001277

Internet

http://www.sciencedirect.com/science/article/pii/S2213671115001277

Similar Items