Neural tube patterning: From a minimal model for rostrocaudal patterning toward an integrated 3D model

Summary: Rostrocaudal patterning of the neural tube is a defining event in vertebrate brain development. This process is driven by morphogen gradients which specify the fate of neural progenitor cells, leading to the partitioning of the tube. Although this is extensively studied experimentally, an i...

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Bibliographic Details
Main Authors: Max Brambach, Ariane Ernst, Sara Nolbrant, Janelle Drouin-Ouellet, Agnete Kirkeby, Malin Parmar, Victor Olariu
Format: Article
Language:English
Published: Elsevier 2021-06-01
Series:iScience
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004221005277