MIF family members cooperatively inhibit p53 expression and activity.

MIF family members cooperatively inhibit p53 expression and activity.

The tumor suppressor p53 is induced by genotoxic stress in both normal and transformed cells and serves to transcriptionally coordinate cell cycle checkpoint control and programmed cell death responses. Macrophage migration inhibitory factor (MIF) is an autocrine and paracrine acting cytokine/growth...

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Bibliographic Details
Main Authors: Stephanie E Brock, Beatriz E Rendon, Dan Xin, Kavitha Yaddanapudi, Robert A Mitchell
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4059697?pdf=render

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http://europepmc.org/articles/PMC4059697?pdf=render

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