CD33 rs2455069 SNP: Correlation with Alzheimer’s Disease and Hypothesis of Functional Role

CD33 rs2455069 SNP: Correlation with Alzheimer’s Disease and Hypothesis of Functional Role

The <i>CD33</i> gene encodes for a member of the sialic-acid-binding immunoglobulin-type lectin (Siglec) family, and is one of the top-ranked Alzheimer’s disease (AD) risk genes identified by genome-wide association studies (GWAS). Many <i>CD33</i> polymorphisms are associate...

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Bibliographic Details
Main Authors: Fabiana Tortora, Antonella Rendina, Antonella Angiolillo, Alfonso Di Costanzo, Francesco Aniello, Aldo Donizetti, Ferdinando Febbraio, Emilia Vitale
Format: Article
Language:English
Published: MDPI AG 2022-03-01
Series:International Journal of Molecular Sciences
Subjects:
CD33
Alzheimer’s disease
sialic acid
phagocytosis
Online Access:https://www.mdpi.com/1422-0067/23/7/3629

Internet

https://www.mdpi.com/1422-0067/23/7/3629

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