Design, synthesis, molecular docking studies and biological evaluation of thiazole carboxamide derivatives as COX inhibitors

Abstract Background Nonsteroidal anti-inflammatory drugs (NSAIDs) have been the most commonly used class of medications worldwide for the last three decades. Objectives This study aimed to design and synthesize a novel series of methoxyphenyl thiazole carboxamide derivatives and evaluate their cyclo...

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Bibliographic Details
Main Authors: Mohammed Hawash, Nidal Jaradat, Murad Abualhasan, Murat Kadır Şüküroğlu, Mohammed T. Qaoud, Deniz Cansen Kahraman, Heba Daraghmeh, Leen Maslamani, Mais Sawafta, Ala Ratrout, Linda Issa
Format: Article
Language:English
Published: BMC 2023-03-01
Series:BMC Chemistry
Subjects:
Online Access:https://doi.org/10.1186/s13065-023-00924-3