Design, synthesis, molecular docking studies and biological evaluation of thiazole carboxamide derivatives as COX inhibitors

Design, synthesis, molecular docking studies and biological evaluation of thiazole carboxamide derivatives as COX inhibitors

Abstract Background Nonsteroidal anti-inflammatory drugs (NSAIDs) have been the most commonly used class of medications worldwide for the last three decades. Objectives This study aimed to design and synthesize a novel series of methoxyphenyl thiazole carboxamide derivatives and evaluate their cyclo...

Full description

Bibliographic Details
Main Authors: Mohammed Hawash, Nidal Jaradat, Murad Abualhasan, Murat Kadır Şüküroğlu, Mohammed T. Qaoud, Deniz Cansen Kahraman, Heba Daraghmeh, Leen Maslamani, Mais Sawafta, Ala Ratrout, Linda Issa
Format: Article
Language:English
Published: BMC 2023-03-01
Series:BMC Chemistry
Subjects:
Thiazole
NSAIDs
COX
HCT116
Molecular docking
Online Access:https://doi.org/10.1186/s13065-023-00924-3

Similar Items

Similar Items