Effects of avitinib on the pharmacokinetics of osimertinib in vitro and in vivo in rats

Effects of avitinib on the pharmacokinetics of osimertinib in vitro and in vivo in rats

Background Avitinib is one type of the third‐generation epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs) for the treatment of non‐small cell lung cancer (NSCLC) with EGFR mutations. The purpose of this study was to investigate the effect of avitinib on the pharmacokinetics o...

Full description

Bibliographic Details
Main Authors: Qingjun Wu, Hui Jiang, Shuanghu Wang, Dapeng Dai, Feifei Chen, Deru Meng, Peiwu Geng, Hongfeng Tong, Yunfang Zhou, Debiao Pan, Quan Zhou, Chunjie Wang
Format: Article
Language:English
Published: Wiley 2020-10-01
Series:Thoracic Cancer
Subjects:
Avitinib
drug‐drug interaction
osimertinib
pharmacokinetics
Online Access:https://doi.org/10.1111/1759-7714.13587

Internet

https://doi.org/10.1111/1759-7714.13587

Similar Items