instaGRAAL: chromosome-level quality scaffolding of genomes using a proximity ligation-based scaffolder

instaGRAAL: chromosome-level quality scaffolding of genomes using a proximity ligation-based scaffolder

Abstract Hi-C exploits contact frequencies between pairs of loci to bridge and order contigs during genome assembly, resulting in chromosome-level assemblies. Because few robust programs are available for this type of data, we developed instaGRAAL, a complete overhaul of the GRAAL program, which has...

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Bibliographic Details
Main Authors: Lyam Baudry, Nadège Guiglielmoni, Hervé Marie-Nelly, Alexandre Cormier, Martial Marbouty, Komlan Avia, Yann Loe Mie, Olivier Godfroy, Lieven Sterck, J. Mark Cock, Christophe Zimmer, Susana M. Coelho, Romain Koszul
Format: Article
Language:English
Published: BMC 2020-06-01
Series:Genome Biology
Subjects:
Ectocarpus
Hi-C scaffolding
Hi-C, genome assembly
MCMC
GPU
Desmarestia herbacea
Online Access:http://link.springer.com/article/10.1186/s13059-020-02041-z

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http://link.springer.com/article/10.1186/s13059-020-02041-z

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