Subregional Structural Alterations in Hippocampus and Nucleus Accumbens Correlate with the Clinical Impairment in Patients with Alzheimer’s Disease Clinical Spectrum: Parallel Combining Volume and Vertex-Based Approach

Subregional Structural Alterations in Hippocampus and Nucleus Accumbens Correlate with the Clinical Impairment in Patients with Alzheimer’s Disease Clinical Spectrum: Parallel Combining Volume and Vertex-Based Approach

Deep gray matter structures are associated with memory and other important functions that are impaired in Alzheimer’s disease (AD) and mild cognitive impairment (MCI). However, systematic characterization of the subregional atrophy and deformations in these structures in AD and MCI still need more i...

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Bibliographic Details
Main Authors: Xiuling Nie, Yu Sun, Suiren Wan, Hui Zhao, Renyuan Liu, Xueping Li, Sichu Wu, Zuzana Nedelska, Jakub Hort, Zhao Qing, Yun Xu, Bing Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-08-01
Series:Frontiers in Neurology
Subjects:
Alzheimer’s disease
mild cognitive impairment
deep gray matter structures
surface alteration
vertex analysis
Online Access:http://journal.frontiersin.org/article/10.3389/fneur.2017.00399/full

Internet

http://journal.frontiersin.org/article/10.3389/fneur.2017.00399/full

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