Fusobacterium periodonticum BCT protein targeting glucose metabolism to promote the epithelial-mesenchymal transition of esophageal cancer cells by lactic acid

Fusobacterium periodonticum BCT protein targeting glucose metabolism to promote the epithelial-mesenchymal transition of esophageal cancer cells by lactic acid

Abstract Background The cancer microbiota was considered the main risk factor for cancer progression. We had proved that Fusobacterium periodonticum (F.p) was higher abundance in Esophageal cancer(EC)tissues. Bioinformation analysis found that BCT was a key virulence protein of F.p. However, little...

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Detalhes bibliográficos
Principais autores: Xinxin Guo, Ping Wan, Weitao Shen, Mingjun Sun, Zhenyan Peng, Yinghao Liao, Yang Huang, Ran Liu
Formato: Artigo
Idioma:English
Publicado em: BMC 2024-04-01
coleção:Journal of Translational Medicine
Assuntos:
Fusobacterium periodonticum
Esophageal cancer
Glycolysi
TLR4/Akt/HIF-1α
EMT
Acesso em linha:https://doi.org/10.1186/s12967-024-05157-z

Internet

https://doi.org/10.1186/s12967-024-05157-z

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