Biomimetic hydrogel supports initiation and growth of patient-derived breast tumor organoids

Biomimetic hydrogel supports initiation and growth of patient-derived breast tumor organoids

Patient-derived tumour organoids are important preclinical models but suffer from variability from the use of basement-membrane extract and cell contamination. Here, the authors report on the development of mimetic nanofibrilar hydrogel which supports tumour organoid growth with reduced batch variab...

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Bibliographic Details
Main Authors: Elisabeth Prince, Jennifer Cruickshank, Wail Ba-Alawi, Kelsey Hodgson, Jillian Haight, Chantal Tobin, Andrew Wakeman, Alona Avoulov, Valentina Topolskaia, Mitchell J. Elliott, Alison P. McGuigan, Hal K. Berman, Benjamin Haibe-Kains, David W. Cescon, Eugenia Kumacheva
Format: Article
Language:English
Published: Nature Portfolio 2022-03-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-022-28788-6

Internet

https://doi.org/10.1038/s41467-022-28788-6

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