quantitative assessment of the influence of cytochrome P450 1A2 gene polymorphism and colorectal cancer risk.

Cytochrome P450 1A2 (CYP1A2) encodes a member of the cytochrome P450 superfamily of enzymes, which play a central role in activating and detoxifying many carcinogens and endogenous compounds thought to be involved in the development of colorectal cancer (CRC). The CYP1A2*C (rs2069514) and CYP1A2*F (...

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Bibliographic Details
Main Authors: Yuan Zhao, Zi-Xian Chen, Abudouaini Rewuti, Yu-Shui Ma, Xiao-Feng Wang, Qing Xia, Da Fu, Yu-Song Han
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3741149?pdf=render