Human umbilical cord mesenchymal stromal cell-derived exosomes protect against MCD-induced NASH in a mouse model

Human umbilical cord mesenchymal stromal cell-derived exosomes protect against MCD-induced NASH in a mouse model

Abstract Background and aims Human umbilical cord mesenchymal stem cells (hUC-MSCs) are increasingly being studied in clinical trials of end-stage liver disease because of their good tissue repair and anti-inflammatory effects. hUC-MSC exosomes are vesicles with spherical structures secreted by cell...

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Bibliographic Details
Main Authors: Ying Shi, Xiaoguang Yang, Shuyue Wang, Yulun Wu, Lihua Zheng, Yufang Tang, Yanhang Gao, Junqi Niu
Format: Article
Language:English
Published: BMC 2022-11-01
Series:Stem Cell Research & Therapy
Subjects:
Nonalcoholic steatohepatitis
hUC-MSC exosomes
PPARα
MCD mouse model
Online Access:https://doi.org/10.1186/s13287-022-03201-7

Internet

https://doi.org/10.1186/s13287-022-03201-7

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