MEOX2-mediated regulation of Cathepsin S promotes cell proliferation and motility in glioma

Abstract Nuclear transcription factor Mesenchyme Homeobox 2 (MEOX2) is a homeobox gene that is originally discovered to suppress the growth of vascular smooth muscle and endothelial cells. However, whether or not it is connected to cancer is yet unknown. Here, we report that MEOX2 functions as a tum...

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Bibliographic Details
Main Authors: Ji Wang, Yanming Chen, Qing Wang, Hui Xu, Chunwang Wu, Qianqian Jiang, Guoqing Wu, Honglong Zhou, Zongyu Xiao, Ying Chen, Tan Zhang, Qing Lan
Format: Article
Language:English
Published: Nature Publishing Group 2022-04-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-022-04845-2