Role of hyperbaric oxygen therapy in PDGF-BB-mediated astrogliosis in traumatic brain injury rats associated with ERK1/2 signaling pathway inhibition

Role of hyperbaric oxygen therapy in PDGF-BB-mediated astrogliosis in traumatic brain injury rats associated with ERK1/2 signaling pathway inhibition

Abstract Background Hyperbaric oxygen (HBO) plays positive roles in the therapy of traumatic brain injury (TBI); however, the mechanism underlying its effects on TBI is largely unknown. The study aims to elucidate the molecular mechanism implicated with the interaction between platelet-derived growt...

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Bibliographic Details
Main Authors: Guanghui Xiu, Xiuling Li, Qiang Li, Yunyu Yin, Qiqi Tang, Jintao Li, Jiaying Ling, Bin Ling, Ying Yang
Format: Article
Language:English
Published: BMC 2023-02-01
Series:European Journal of Medical Research
Subjects:
Hyperbaric oxygen therapy
Traumatic brain injury
Platelet-derived growth factor
Extracellular signal-regulated kinase 1/2
Astrogliosis
Neural regeneration
Online Access:https://doi.org/10.1186/s40001-023-01062-1

Internet

https://doi.org/10.1186/s40001-023-01062-1

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