Acute liver steatosis translationally controls the epigenetic regulator MIER1 to promote liver regeneration in a study with male mice

Early lipid accumulation is thought to contribute to liver regeneration through unclear functional mechanisms. Here the authors identify an epigenetic regulator, MIER1, that bridges the acute lipid accumulation and cell cycle gene transcription during liver regeneration after surgical resection in m...

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Bibliographic Details
Main Authors: Yanhao Chen, Lanlan Chen, Xiaoshan Wu, Yongxu Zhao, Yuchen Wang, Dacheng Jiang, Xiaojian Liu, Tingting Zhou, Shuang Li, Yuda Wei, Yan Liu, Cheng Hu, Ben Zhou, Jun Qin, Hao Ying, Qiurong Ding
Format: Article
Language:English
Published: Nature Portfolio 2023-03-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-023-37247-9