Sex Differences in Genomic Features of Hepatitis B–Associated Hepatocellular Carcinoma With Distinct Antitumor ImmunitySummary

Sex Differences in Genomic Features of Hepatitis B–Associated Hepatocellular Carcinoma With Distinct Antitumor ImmunitySummary

Background & Aims: Aflatoxin exposure increases the risk for hepatocellular carcinoma (HCC) in hepatitis B virus (HBV)-infected individuals, particularly males. We investigated sex-based differences in the HCC genome and antitumor immunity. Methods: Whole-genome, whole-exome, and RNA sequenc...

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Bibliographic Details
Main Authors: Chungui Xu, Shaoyan Cheng, Kun Chen, Qianqian Song, Chang Liu, Chunsun Fan, Ruochan Zhang, Qing Zhu, Zhiyuan Wu, Yuting Wang, Jian Fan, Hongwei Zheng, Lingling Lu, Taoyang Chen, Hong Zhao, Yuchen Jiao, Chunfeng Qu
Format: Article
Language:English
Published: Elsevier 2023-01-01
Series:Cellular and Molecular Gastroenterology and Hepatology
Subjects:
Sex Hormones
Aflatoxin
DNA Double-Strand Break
Immune Checkpoints
HBV
Online Access:http://www.sciencedirect.com/science/article/pii/S2352345X2200220X

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http://www.sciencedirect.com/science/article/pii/S2352345X2200220X

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